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Zinc-binding alcohol dehydrogenase domain-containing protein 1 (ZADH1, PTGR2)
Function:
1) NADPH-dependent oxidoreductase
2) despite its name, does NOT bind Zn+2
Structure:
- despite its name, does not belong to Zn+2-containing alcohol dehydrogenase family
- monomer
- belongs to the NADP-dependent oxidoreductase L4BD family
Compartment: cytoplasm
Alternative splicing: named isoforms=2
Expression:
- widely expressed
General
oxidoreductase
Properties
SIZE: MW = 38 kD
entity length = 351 aa
COMPARTMENT: cytoplasm
MOTIF: cofactor-binding site [162-168]
COFACTOR-BOUND: NAD
cofactor-binding site [188-208]
COFACTOR-BOUND: NAD
Database Correlations
OMIM 608642
UniProt Q8N8N7
Pfam PF00107
ENZYME 1.-.-.-
References
UniProt :accession Q8N8N7