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Yemenite deaf-blind hypopigmentation syndrome

Genetics: - associated with defects in SOX10 Clinical manifestations: - cutaneous hypopigmented & hyperpigmented spots & patches, microcornea, coloboma & severe hearing loss - another case observed in a girl with similar skin symptoms & hearing loss but without microcornea or coloboma is reported as a mild form of this syndrome

General

genetic syndrome (multisystem disorder)

Database Correlations

OMIM 601706

References

UniProt :accession P56693