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XPA-binding protein 2 (HCNP protein) (XAB2 HCNP KIAA1177 PP3898)
Function:
- role in transcription-coupled repair, transcription & pre-mRNA splicing
- associates with RNA polymerase 2, the transcription-coupled repair-specific proteins CKN1/CSA & ERCC6/CSB, & XPA
- identified in the spliceosome C complex
Structure: contains 14 HAT repeats
Compartment:
- nucleus (putative)
- detected in splicing complex carrying pre-mRNA (putative)
General
nuclear protein
Properties
SIZE: MW = 100 kD
entity length = 855 aa
COMPARTMENT: cell nucleus
MOTIF: HAT {15-47}
HAT {48-80}
HAT {90-122}
HAT {124-158}
HAT {160-192}
HAT {198-230}
HAT {235-268}
HAT {270-305}
HAT {369-407}
HAT {498-530}
HAT {532-566}
HAT {571-605}
HAT {643-677}
HAT {679-713}
Database Correlations
UniProt Q9HCS7
Pfam PF07719
References
UniProt :accession Q9HCS7
Component-of
spliceosome C complex