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wound infection
Wounds can be classified as infected when the wound tissue contains >= 10E5 microorganisms per gram of tissue.
Classification:
1) Infection (Clinical)
- the presence of bacteria or other microorganisms in sufficient quantity to overwhelm the tissue defenses & produce the inflammatory signs of infection
- purulent exudate, odor, erythema, warmth, tenderness, edema, pain, fever
- elevated white cell count
2) Local Clinical Infection.
- clinical infection that is confined to the wound & within a few millimeters of its margins
3) Systemic Clinical Infection.
- clinical infection that extends beyond the margins of the wound.
Clinical manifestations:
- clinical signs of infection may not be present, especially in the immunocompromised patient or the patient with a chronic wound
Management:
- use Silvadene for wounds with > 1 million CFU/g tissue or any infection with beta-hemolytic Streptococci
- consider topical antibiotic for clean wounds that are not healing after 2-4 weeks of optimal care
- systemic antibiotics for signs of spreading infection, cellulitis, or osteomyelitis
- clindamycin or TMP/SMX 92% effective [1]
Specific
surgical site infection
General
infection (infectious disease)
References
- Talan DA et al.
A randomized trial of clindamycin versus trimethoprim-
sulfamethoxazole for uncomplicated wound infection.
Clin Infect Dis 2016 Mar 29
PMID: 27025829