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wnt proto-oncogene protein or int proto-oncogene protein

Function: - thought to be involved in developmental regulation - Wnt proteins appear to be functionally distinct - canonical Wnts (Wnt1, Wnt3A, Wnt8) stabilize beta-catenin (see wnt-1 signaling & Wnt/beta-catenin induced genes) - non-canonical Wnts (Wnt4, Wnt5A, Wnt11) activate other pathways - several Wnts have properties of both

Related

frizzled homolog protein wnt family proto-oncogene Wnt-1 signalling

Specific

protein Wnt-11 (WNT11) Wnt-13 proto-oncogene protein protein Wnt-2b; (WNT2B, WNT13) Wnt-14 proto-oncogene protein; protein Wnt-9a (WNT9A, WNT14) wnt1 proto-oncogene protein; int1 proto-oncogene protein; wingless (WNT1, INT1) wnt2 proto-oncogene protein (IRP protein, int-1-related protein, WNT2, INT1L1, IRP) wnt2B proto-oncogene protein wnt3 proto-oncogene protein or int4 proto-oncogene protein wnt3A proto-oncogene protein wnt4 proto-oncogene protein wnt5A proto-oncogene protein wnt5B proto-oncogene protein wnt6 proto-oncogene protein wnt7A proto-oncogene protein wnt7B proto-oncogene protein wnt8A proto-oncogene protein wnt8B proto-oncogene protein wnt9A proto-oncogene protein wnt9B proto-oncogene protein wnt10A proto-oncogene protein wnt10B proto-oncogene protein (wnt10B, wnt12) wnt15 proto-oncogene protein; protein Wnt-9b; Wnt-14b (WNT9B, WNT14B, WNT15, UNQ6973/PRO21956) wnt16 proto-oncogene protein; protein Wnt-16 (WNT16)

General

glycoprotein proto oncogene protein

Properties

MOTIF: N-glycosylation site (SEVERAL) cysteine-rich region

References

  1. prosite :accession PS00246