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Wnt/beta-catenin induced genes

genes induced by canonical wnt pathway/beta-catenin include: - c-myc - cyclin D - tcf-1 - lef1 - PPar-delta - c-jun - fra-1 - uPAR - matrix metalloproteinase 7 (MMP-7) - matrix metalloproteinase 26 (MMP-26) - axin-2 - Nr-CAM - ITF-2 - gastrin - CD44 - ephrin-B - BMP4 - claudin-1 - survivin - VEGF - FGF4 - FGF18 - FoxN1 - Id2 - twist - stromelysin - WISP-1,2 - brachyury - proglucagon - cyclooxygenase-2 - neurogenin 1 - proliferin-2,3 - IGF-I,II - MDR1 - interleukin 6 - betaTrCP - pitx2 - ret - connexin43 genes with reduced expression: - osteocalcin - periostin - E-cadherin

Related

beta catenin wnt proto-oncogene protein or int proto-oncogene protein

General

unclassified gene

References

http://www.stanford.edu/~rnusse/pathways/targets.html