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wnt2 proto-oncogene protein (IRP protein, int-1-related protein, WNT2, INT1L1, IRP)
Function:
- ligand for members of the frizzled family
- probable developmental protein
- may be a signaling molecule which affects development of discrete regions of tissues
- likely to signal over only few cell diameters
Structure: belongs to the Wnt family
Compartment:
- secreted, extracellular space, extracellular matrix
Expression:
- expressed in brain in the thalamus, in fetal & adult lung & in placenta
General
secreted protein
wnt proto-oncogene protein or int proto-oncogene protein
Properties
SIZE: entity length = 360 aa
MW = 40 kD
COMPARTMENT: extracellular compartment
MOTIF: signal sequence {1-25}
N-glycosylation site {N295}
Database Correlations
OMIM 147870
UniProt P09544
Pfam PF00110
Entrez Gene 7472
Kegg hsa:7472
References
- Entrez Gene :accession 7472
- UniProt :accession P09544