wings apart-like protein homolog (friend of EBNA2 protein, WAPAL, FOE, KIAA0261, WAPL)

Function: - may play a role in cell growth - isoform 2 interacts with Epstein-Barr virus EBNA2 Structure: contains 1 WAPL domain Compartment: isoform 2: nucleus Alternative splicing: named isoforms=3 Expression: - isoform 2 is widely espressed with a high level in skeletal muscle & heart Pathology: - isoform 1 is highly expressed in cervical cancer

General

nuclear protein phosphoprotein

Properties

SIZE: MW = 133 kD entity length = 1190 aa COMPARTMENT: cell nucleus MOTIF: Ser phosphorylation site {S77} Ser phosphorylation site {S221} Ser phosphorylation site {S226} coiled coil {260-286} Ser phosphorylation site {S459} Ser phosphorylation site {S461} WAPL {626-1169} MOTIF: coiled coil {749-782}

Database Correlations

UniProt Q7Z5K2 Pfam PF07814

References

UniProt :accession Q7Z5K2