WAP four-disulfide core domain protein 5 (protease inhibitor WAP1, p53-responsive gene 5 protein, WFDC5, PRG5, WAP1, NQ3036/PRO9842)

Function: - putative acid-stable serine proteinase inhibitor Structure: contains 2 WAP domains Compartment: secreted Alternative splicing: named isoforms=2

Properties

SIZE: MW = 24 kD entity length = 224 aa COMPARTMENT: extracellular compartment MOTIF: signal sequence {1-24} WAP 1 {30-74} MOTIF: cysteine residue {C34} MODIFICATION: cysteine residue {C62} cysteine residue {C41} MODIFICATION: cysteine residue {C66} cysteine residue {C49} MODIFICATION: cysteine residue {C61} cysteine residue {C55} MODIFICATION: cysteine residue {C70} cysteine residue {C61} MODIFICATION: cysteine residue {C49} cysteine residue {C62} MODIFICATION: cysteine residue {C34} cysteine residue {C66} MODIFICATION: cysteine residue {C41} cysteine residue {C70} MODIFICATION: cysteine residue {C55} WAP 2 {77-121} MOTIF: cysteine residue {C81} MODIFICATION: cysteine residue {C109} cysteine residue {C88} MODIFICATION: cysteine residue {C113} cysteine residue {C96} MODIFICATION: cysteine residue {C108} cysteine residue {C102} MODIFICATION: cysteine residue {C117} cysteine residue {C108} MODIFICATION: cysteine residue {C96} cysteine residue {C109} MODIFICATION: cysteine residue {C81} cysteine residue {C113} MODIFICATION: cysteine residue {C88} cysteine residue {C117} MODIFICATION: cysteine residue {C102} INHIBITS: serine protease

Database Correlations

OMIM 605161 UniProt Q8TCV5 Pfam PF00095

References

UniProt :accession Q8TCV5