Search
VWFA & cache domain-containing protein 1 (Cache domain-containing protein 1, CACHD1, KIAA1573, VWCD1)
Function:
- may regulate voltage-dependent Ca+2 channels
Structure:
- belongs to the Ca+2 channel subunit alpha-2/delta family
- contains 2 cache domains
- contains 1 VWFA domain
Compartment: membrane (putative)
Alternative splicing: named isoforms=2
General
glycoprotein
phosphoprotein
voltage-dependent Ca+2 channel-alpha
Properties
SIZE: entity length = 1274 aa
MW = 142 kD
COMPARTMENT: cellular membrane
MOTIF: signal sequence {1-35}
N-glycosylation site {N145}
VWFA domain {228-443}
Cache 1 {453-532}
Cache 2 {772-853}
cysteine-rich region {943-982}
transmembrane domain {1096-1116}
Ser phosphorylation site {S1178}
histidine-rich region {1243-1260}
MOTIF: histidine residue (SEVERAL)
Database Correlations
UniProt Q5VU97
PFAM correlations
References
UniProt :accession Q5VU97