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VPS10 domain-containing protein (VPS10)
Family of proteins containing VPS10-domain involved in endosomal trafficking. Yeast apparently contains a single VPS10 protein.
Related
vacuolar protein sorting-associated protein (VPS)
vacuolar sorting protein
vacuole
Specific
low-density lipoprotein receptor relative with 11 ligand-binding repeats; sortilin-related receptor; sorting protein-related receptor containing LDLR class A repeats; LDLR relative with 11 ligand-binding repeats (SorLA, SorLA-1, LR11, SORL1)
neurotensin receptor 3 (sortilin, SORT1)
VPS10 domain-containing receptor SorCS (SORCS)
General
cell surface receptor
glycoprotein
Properties
COMPARTMENT: plasma membrane
MOTIF: ligand-binding site
glycosylation site
transmembrane domain
References
- Small SA, Kent K, Pierce A, Leung C, Kang MS, Okada H,
Honig L, Vonsattel JP, Kim TW.
Model-guided microarray implicates the retromer complex in
Alzheimer's disease.
Ann Neurol. 2005 Dec;58(6):909-19.
PMID: 16315276