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vortex keratopathy (corneal verticillata)
Etiology:
- adverse effect of amiodarone
- adverse effect of hydroxychloroquine
Epidemiology:
- common adverse effect of amiodarone
Pathology:
- whorl-like pattern of gray or golden brown deposits (hydroxychloroquine) Clinical manifestaitons:
- halos around lights (bilateral)
Special laboratory:
- slit-lamp examination of the anterior segment:
- whorl-like pattern of corneal epithelial deposits bilaterally
Management:
- discontinue amiodarone
- wear sunglasses for symptomatic relief
General
corneal disease (keratopathy)
References
- Chan TC, Jhanji V.
Images in clinical medicine. Amiodarone-induced vortex
keratopathy.
N Engl J Med. 2015 Apr 23;372(17):1656
PMID: 25901429
http://www.nejm.org/doi/full/10.1056/NEJMicm1406501
- Geriatric Review Syllabus, 9th edition (GRS9)
Medinal-Walpole A, Pacala JT, Porter JF (eds)
American Geriatrics Society, 2016