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vomeronasal type-1 receptor 5; V1r-like receptor 5; hGPCR26 (VN1R5, V1RL5)

Function: - putative pheromone receptor Structure: - belongs to the G-protein coupled receptor 1 family Compartment: - cell membrane; multi-pass membrane protein Polymorphism: - allele VN1R5*2 with a truncating mutation in position 46, found with a frequency of about 32% Genetics: - chimpanzee & orangutan orthologous proteins do not exist, their genes are pseudogenes

Related

vomer

General

evolutionary divergent human protein glycoprotein vomeronasal type-1 receptor (V1r-like receptor, VN1R)

Properties

SIZE: MW = 41 kD entity length = 357 aa COMPARTMENT: cellular membrane MOTIF: exoplasmic domain {1-3} transmembrane domain {4-24} cytoplasmic loop {25-52} transmembrane domain {53-73} exoplasmic loop {74-81} transmembrane domain {82-102} cytoplasmic loop {103-130} transmembrane domain {131-151} exoplasmic loop {152-163} transmembrane domain {164-184} cytoplasmic loop {185-269} transmembrane domain {270-290} exoplasmic loop {291-300} MOTIF: N-glycosylation site {N297} transmembrane domain {301-321} cytoplasmic domain {322-357}

Database Correlations

UniProt Q7Z5H4 Pfam PF03402

References

  1. UniProt :accession Q7Z5H4
  2. Protein Spotlight No one nose - Issue 61 of August 2005 http://www.expasy.org/spotlight/back_issues/sptlt061.shtml