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vomeronasal type-1 receptor 4 (V1r-like receptor 4, hGPCR27, VN1R4, V1RL4)
Function:
- putative pheromone receptor
Structure:
- belongs to the G-protein coupled receptor 1 family
Compartment: cell membrane
Polymorphism: various VN1R4 alleles are known
Genetics:
- chimpanzee & gorilla orthologous proteins do not exist; their genes are pseudogenes
General
evolutionary divergent human protein
glycoprotein
vomeronasal type-1 receptor (V1r-like receptor, VN1R)
Properties
SIZE: MW = 34 kD
entity length = 301 aa
COMPARTMENT: cellular membrane
MOTIF: exoplasmic domain {1-5}
transmembrane domain {6-26}
cytoplasmic loop {27-48}
transmembrane domain {49-69}
exoplasmic loop {70-88}
transmembrane domain {89-109}
cytoplasmic loop {110-126}
transmembrane domain {127-147}
exoplasmic loop {148-185}
MOTIF: N-glycosylation site {N154}
N-glycosylation site {N157}
transmembrane domain {186-206}
cytoplasmic loop {207-234}
transmembrane domain {235-255}
exoplasmic loop {256-264}
transmembrane domain {265-285}
cytoplasmic domain {286-301}
Database Correlations
UniProt Q7Z5H5
Pfam PF03402
Entrez Gene 317703
Kegg hsa:317703
References
- UniProt :accession Q7Z5H5
- Protein Spotlight
No one nose - Issue 61 of August 2005
http://www.expasy.org/spotlight/back_issues/sptlt061.shtml