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villin-like protein (VILL)
Function: possible tumor suppressor
Structure:
- belongs to the villin/gelsolin family
- contains 6 gelsolin-like repeats
- contains 1 HP (headpiece) domain
Alternative splicing: named isoforms=2
Expression: ubiquitously expressed in 16 tissues examined
General
villin
Properties
SIZE: entity length = 856 aa
MW = 96 kD
COMPARTMENT: cytoplasm
MOTIF: Gelsolin-like {22-74}
Gelsolin-like {146-186}
Gelsolin-like {263-307}
Gelsolin-like {401-450}
Ca+2-binding site
binding site (2)
FOR-BINDING-OF: F-actin
Gelsolin-like {521-561}
Gelsolin-like {624-665}
villin headpiece domain {790-856}
Database Correlations
UniProt O15195
PFAM correlations
Entrez Gene 50853
Kegg hsa:50853
References
- UniProt :accession O15195
- Entrez Gene :accession 50853