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villin
Function:
- bundles actin filaments
- severes actin at mM Ca+2
Expression:
- induces microvilli formation in transfected cells
Interactions
molecular events
Related
villin Ag in tissue
Specific
ezrin; p81; cytovillin; Villin-2 (EZR VIL2)
villin-1 (VIL1 VIL)
villin-like protein (VILL)
General
Ca+2 binding protein
cytoskeletal protein
Properties
SIZE: MW = 80-90 kD
COMPARTMENT: cytoplasm
MOTIF: Ca+2-binding site
binding site (2)
FOR-BINDING-OF: F-actin
References
- Molecular Cell Biology (2nd ed) Darnell J; Lodish H
& Baltimore D (eds), Scientific American Books,
WH Freeman, NY 1990, pg 889
- Kelly RB.
Secretion. A question of endosomes.
Nature. 1993 Aug 5;364(6437):487-8.
PMID: 8336787