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verdinexor (Laverdia-CA1)
Indications:
- oral treatment for dogs with lymphoma
Dosage:
- tabs: 2.5 mg, 10 mg, 50 mg
Mechanism of action:
- inhibits nuclear export
General
antiviral agent
antineoplastic agent (chemotherapeutic agent)
References
- FDA News Release. Jan 11, 2021
FDA Conditionally Approves First Oral Tablet to Treat Lymphoma in Dogs.
https://www.fda.gov/news-events/press-announcements/fda-conditionally-approves-first-oral-tablet-treat-lymphoma-dogs
- Perwitasari O, Johnson S, Yan X et al
Verdinexor, a novel selective inhibitor of nuclear export, reduces
influenza a virus replication in vitro and in vivo.
J Virol. 2014 Sep 1;88(17):10228-43.
PMID: 24965445 Free PMC article.