ventral anterior homeobox 2 (VAX2)

Function: - role in eye development, in particular, in specification of the ventral optic vesicle - may regulate axial polarization in the retina Structure: - belongs to the EMX homeobox family - contains 1 homeobox DNA-binding domain Compartment: nucleus (probable) Expression: - in the embryo, expressed in the ventral part of the optic vesicles at 7 weeks

General

homeobox protein transcription factor (TF)

Properties

SIZE: entity length = 290 aa MW = 31 kD COMPARTMENT: cell nucleus MOTIF: glycine-rich region {1-71} homeodomain SITE: 102-161

Database Correlations

OMIM 604295 UniProt Q9UIW0 Pfam PF00046 Entrez Gene 25806 Kegg hsa:25806

References

UniProt :accession Q9UIW0