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vasopressin V3 receptor; vasopressin V1b receptor; AVPR V1b; V1bR; AVPR V3; antidiuretic hormone receptor 1b (AVPR1B, AVPR3, VPR3)

Function: - receptor for arginine vasopressin - activity is mediated by G proteins which activate a phosphatidylinositol-Ca+2 second messenger system Structure: belongs to the G-protein coupled receptor 1 family Compartment: cell membrane

General

glycoprotein vasopressin receptor or antidiuretic hormone [ADH] receptor

Properties

SIZE: entity length = 424 aa MW = 47 kD COMPARTMENT: plasma membrane MOTIF: exoplasmic domain {1-35} MOTIF: N-glycosylation site {N21} transmembrane domain {36-59} cytoplasmic loop {60-71} transmembrane domain {72-93} exoplasmic loop {94-108} MOTIF: cysteine residue {C107} MODIFICATION: cysteine residue {C186} transmembrane domain {109-130} cytoplasmic loop {131-151} transmembrane domain {152-173} exoplasmic loop {174-201} MOTIF: cysteine residue {C186} MODIFICATION: cysteine residue {C107} transmembrane domain {202-222} cytoplasmic loop {223-283} transmembrane domain {284-303} exoplasmic loop {304-321} transmembrane domain {322-341} cytoplasmic domain {342-424}

Database Correlations

OMIM 600264 UniProt P47901 Pfam PF00001 Kegg hsa:553

References

  1. UniProt :accession P47901
  2. SeattleSNPs http://pga.gs.washington.edu/data/avpr1b/