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vasculin (GC-rich promoter-binding protein 1, vascular wall-linked protein, GPBP1, GPBP, SSH6)
Function:
- GC-rich promoter-specific transactivating transcription factor (putative)
- interacts with GTF2B, GTF2F2, RNA polymerase II & TBP
Structure: belongs to the vasculin family
Compartment:
- nucleus
- cytoplasm [2]
Alternative splicing: named isoforms=4
Expression:
- widely expressed
- some isoforms may be specifically expressed in veins & arteries (at protein level)
- isoform 4 is widely expressed
- isoforms 1, 2 & 3 may be specifically expressed in vascular smooth muscle cells
General
transcription factor (TF)
Properties
SIZE: entity length = 473 aa
MW = 53 kD
COMPARTMENT: cytoplasm
cell nucleus
Database Correlations
OMIM 608412
UniProt Q86WP2
Kegg hsa:6505
References
- UniProt :accession Q86WP2
- PMID: 12842993