vacuolar proton translocating ATPase 116 kD subunit a; V-ATPase 116 kD isoform a (ATP6V0A)

Function: - component of the proton channel of V-ATPases

Specific

vacuolar proton translocating ATPase 116 kD subunit a, isoform 2; V-ATPase 116 kD isoform a2 (TJ6, ATP6V0A2) vacuolar proton translocating ATPase 116 kD subunit a, isoform 3; V-ATPase 116 kD isoform a3; osteoclastic proton pump 116 kD subunit; OC-116 kD; OC116; T-cell immune regulator 1; T cell immune response cDNA7 protein (TIRC7, TCIRG1, ATP6N1C, ATP6V0A3) vacuolar proton translocating ATPase 116 kD subunit a, isoform 4; V-ATPase 116 kD isoform a34; vacuolar proton translocating ATPase 116 kD subunit a, kidney isoform (ATP6V0A4, ATP6N1B)

General

adenosine triphosphatase (ATPase) glycoprotein transmembrane 8 protein vacuolar proton translocating ATPase integral membrane subunit; V-ATPase integral membrane subunit

Properties

COMPARTMENT: cellular membrane MOTIF: cytoplasmic domain {N-TERMINAL} exoplasmic loop LOOP#: 1 exoplasmic loop LOOP#: 2 exoplasmic loop LOOP#: 3 exoplasmic loop LOOP#: 4 glycosylation site membrane region active site MOTIF: adenine nucleotide-binding site cytoplasmic domain {C-TERMINAL}

Database Correlations

OMIM 605239 MORBIDMAP 605239 Pfam PF01496

References

Swiss-Prot Q9Y487, Q9HBG4