uroplakin-2; UP2; uroplakin II; UPII (UPK2)

Function: - component of the asymmetric unit membrane (AUM) - role in regulating the assembly of the AUM (putative) - interacts with uroplakin-1a (UPK1A) (putative) Structure: - belongs to the uroplakin-2 family Compartment: - cell membrane; single-pass type 1 membrane protein (putative) - heterodimer formation with UPK1A is a prerequisite to exit out of the endoplasmic reticulum (ER) Expression: - expressed in ureter

General

glycoprotein uroplakin

Properties

SIZE: entity length = 184 aa MW = 19 kD COMPARTMENT: endoplasmic reticulum MOTIF: signal sequence {1-25} N-glycosylation site {N28} N-glycosylation site {N57} N-glycosylation site {N66} transmembrane domain {156-176}

Database Correlations

OMIM 611558 UniProt O00526 Pfam PF07353 Entrez Gene 7379 Kegg hsa:7379

References

UniProt :accession O00526