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uronyl 2-sulfotransferase (UST, DS2ST)
Function:
1) sulfotransferase
2) catalyzes the transfer of sulfate to the position 2 of uronyl residues
3) activity toward iduronyl residues in dermatan sulfate, & weaker activity toward glucuronyl residues of chondroitin sulfate
4) no activity toward desulfated N-resulfated heparin
Structure: belongs to the sulfotransferase 3 family
Compartment: Golgi membrane
Expression: widely expressed
General
glycoprotein
sulfotransferase
Properties
SIZE: MW = 48 kD
entity length = 406 aa
COMPARTMENT: golgi
MOTIF: transmembrane domain {50-70}
N-glycosylation site {N84}
N-glycosylation site {N140}
N-glycosylation site {N155}
N-glycosylation site {N173}
N-glycosylation site {N319}
Database Correlations
UniProt Q9Y2C2
Pfam PF05040
References
UniProt :accession Q9Y2C2