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urine pregnancy test (choriogonadotropin [Presence] in urine)

Indications: - pregnancy Procedure: - use 1st morning urine; it is highest in hcG [3] - allow 10 minutes before reading the test [2] - retesting in a few days may improve sensitivity [3] Methods: - high-sensitivity urine pregnancy tests include: [3] - LifeSign1, One Step dBest, First Response Early Result - RIA for urine hCG has a sensitivity of 0.01 ng/mL (0.13 mIU/mL), 1-2 orders of magnitude more sensitive than the home pregnancy test - RIA detects 90% of pregnancies (> 0.015 ng/mL) by the 1st day of the missed menstrual period & 97% after 1 week Notes: - most home pregnancy tests claim detection limits for hCG of 15-100 mIU/mL [1] - many false negatives are likely when the test is performed on the 1st day of the missed period

Specific

choriogonadotropin in urine

General

pregnancy test point of care test

References

  1. Journal Watch 21(22):179, 2001 Wilcox et al JAMA 286:1759, 2001
  2. Journal Watch 24(6):51, 2004 Cole LA et al, J Obstet Gynecol 190:100, 2004 PMID: 14749643
  3. Home Pregnancy Test Kits Prescriber's Letter 11(4):23 2004 Detail-Document#: 200414 (subscription needed) http://www.prescribersletter.com