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undifferentiated embryonic cell transcription factor 1 (UTF1)
Function:
1) acts as a transcriptional coactivator of ATF2
2) binds to the N-terminal region of ATF2
3) associates with the TFIID complex through interaction with TBP
4) leucine-zipper domain required for coactivation activity, when deleted, UTF1 is able to stimulate transcription from a number of gene promoters
5) phosphorylated
Compartment: nucleus
General
transcription factor (TF)
Properties
SIZE: MW = 36 kD
entity length = 341 aa
COMPARTMENT: cell nucleus
MOTIF: proline-rich region
SITE: 5-273
MOTIF: proline residue (SEVERAL)
leucine zipper
SITE: 279-310
FOR-BINDING-VIA: leucine zipper
Database Correlations
OMIM 604130
UniProt Q5T230
References
UniProt :accession Q5T230