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ularitide
Contraindications:
- of no benefit in acute heart failure
Dosage:
- infusion 5 ng/kg/min (48 hours) [1]
Mechanism of action:
- vasodilator
Clinical trials:
[1]
- decreases mean systolic blood pressure & serum pro-BNP
- no decrease in mortality [1]
Interactions
drug adverse effects of antihypertensive agents
General
vasodilator agent
References
- Packer M, O'Connor C, McMurray JJV et al.
Effect of ularitide on cardiovascular mortality in acute heart
failure.
N Engl J Med 2017 May 18; 376:1956-1964.
PMID: 28402745
- Hauptman PJ.
Disease modification in acute decompensated heart failure.
N Engl J Med. 2017 May 18;376(20):1987-1988.
PMID: 28402754