UDP-glucuronosyltransferase-1 (UDPGT-1)

Function: - conjugates bilirubin Pathology: - enzyme deficient in Crigler-Najjar syndrome.

Specific

UDP-glucuronosyltransferase 1-10; UDPGT 1-10; UGT1*10; UGT1-10; UGT1.10; UDP-glucuronosyltransferase 1-J; UGT-1J; UGT1J; UDP-glucuronosyltransferase 1A10 (UGT1A10, GNT1, UGT1) UDP-glucuronosyltransferase 1-7; UDPGT 1-7; UGT1*7; UGT1-07; UGT1.7; UDP-glucuronosyltransferase 1-G; UGT-1G; UGT1G; UDP-glucuronosyltransferase 1A7 (UGT1A7, GNT1, UGT1) UDP-glucuronosyltransferase 1-8; UDPGT 1-8; UGT1*8; UGT1-08; UGT1.8; UDP-glucuronosyltransferase 1-H; UGT-1H; UGT1H; UDP-glucuronosyltransferase 1A8 (UGT1A8, GNT1, UGT1) UDP-glucuronosyltransferase 1-9; UDPGT 1-9; UGT1*9; UGT1-09; UGT1.9; UDP-glucuronosyltransferase 1-I; UGT-1I; UGT1I; UDP-glucuronosyltransferase 1A9; lugP4 (UGT1A9, GNT1, UGT1) UDP-glucuronosyltransferase-1A (UDPGT-1A, bilirubin-specific isozyme 1, HUG-BR1, UGT1A1, GNT1, UGT1) UDP-glucuronosyltransferase-1C (UDPGT-1C, UGT1A3) UDP-glucuronosyltransferase-1D (UDPGT-1D, UGT1A5, bilirubin-specific isozyme 2, HUG-BR2) UDP-glucuronosyltransferase-1E (UDPGT-1E, UGT1A4) UDP-glucuronosyltransferase-1F (phenol-metabolizing UDP-glucuronosyltransferase, UGT1A6, GNT1, UGT1UDPGT-1F)

General

UDP-glucuronosyltransferase (UDPGT) glycoprotein membrane protein

Properties

COMPARTMENT: cellular membrane MOTIF: glycosylation site membrane region active site

References

- Sedlak TW, Snyder SH. Messenger molecules & cell death: therapeutic implications. JAMA. 2006 Jan 4;295(1):81-9. PMID: 16391220