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UBX1325
Indications:
- diabetic macular edema
- neovascular age-related macular degeneration [1]
Mechanism of action:
- UBX1325 binds to Bcl-xL & selectively induces apoptosis in senescent cells [1]
- a single dose of UBX1325 improves visual acuity in patients with diabetic macular edema or neovascular age-related macular degeneration [1]
General
ophthalmic agent (eyedrops)
References
- Bankhead C
'Senolytic' Therapy Shows Promise in Neovascular Eye Disease.
Clearing out dying cells, approach has implications far beyond ophthalmology.
MedPage Today July 14, 2022
https://www.medpagetoday.com/meetingcoverage/asrs/99734