Search
histone demethylase UTY; ubiquitously transcribed TPR protein on the Y chromosome; ubiquitously transcribed Y chromosome tetratricopeptide repeat protein (UTY)
Function:
- histone demethylase (putative)
- interacts with TLE1 & TLE2 (putative)
Cofactor:
- ascorbate (putative)
- Fe+2 (putative)
Structure:
- belongs to the UTX family
- contains 1 JmjC domain
- contains 8 TPR repeats
Compartment: nucleus (putative)
Alternative splicing:
- named isoforms=3
- additional isoforms seem to exist
General
histone demethylase
tetratricopeptide repeat protein
Y chromosome protein
Properties
SIZE: entity length = 1347 aa
MW = 150 kD
COMPARTMENT: cell nucleus
MOTIF: tetratricopeptide repeat {90-123}
tetratricopeptide repeat {127-160}
tetratricopeptide repeat {167-196}
tetratricopeptide repeat {202-235}
tetratricopeptide repeat {247-280}
tetratricopeptide repeat {281-314}
tetratricopeptide repeat {315-348}
tetratricopeptide repeat {349-382}
JmjC {1042-1205}
Database Correlations
OMIM 400009
UniProt O14607
PFAM correlations
Entrez Gene 7404
Kegg hsa:7404
References
UniProt :accession O14607