ubiquitin carboxyl-terminal hydrolase 17-like protein 23 (USP17L23)

Structure: - belongs to the peptidase C19 family, USP17 subfamily Compartment: - nucleus (putative) - endoplasmic reticulum (putative) Genetics: - the RS447 megasatellite DNA is a highly polymorphic conserved tandem repetitive sequence which contains a copy of USP17 - it is present with an interindividual variation in copy number & between 20-103 copies can be found on chromosome 4 & chromosome 8 Note: - product of a dubious gene prediction

General

nuclear protein ubiquitin C-terminal hydrolase; UCH; ubiquitin thiolesterase; ubiquitin-specific processing protease; deubiquitinating enzyme

Properties

SIZE: entity length = 183 aa MW = 20 kD COMPARTMENT: cell nucleus MOTIF: active site MOTIF: cysteine residue

Database Correlations

UniProt D6RBM5 Pfam PF00443

References

UniProt :accession D6RBM5