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U4/U6.U5 tri-snRNP-associated protein 1 (U4/U6.U5 tri-snRNP-associated 110 kD protein, squamous cell carcinoma antigen recognized by T cells 1, SART-1, hSART-1, hSnu66, SART1)

Function: 1) mRNA splicing (putative) 2) DNA-binding (putative) 3) component of a tri-snRNP complex Compartment: found in the nucleus of proliferating cells Alternative splicing: named isoforms=1 Expression: ubiquitously expressed

General

DNA-binding protein phosphoprotein U4/U6.U5 tri-snRNP-associated protein

Properties

SIZE: MW = 90 kD entity length = 800 aa COMPARTMENT: cell nucleus MOTIF: coiled coil {157-231} Thr phosphorylation site {T392} RNA-binding motif FOR-BINDING-OF: ribonucleic acid DNA-binding motif coiled coil {490-533}

Database Correlations

OMIM 605941 UniProt O43290 Pfam PF03343

References

UniProt :accession O43290

Component-of

spliceosome C complex