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U4/U6.U5 tri-snRNP-associated protein 1 (U4/U6.U5 tri-snRNP-associated 110 kD protein, squamous cell carcinoma antigen recognized by T cells 1, SART-1, hSART-1, hSnu66, SART1)
Function:
1) mRNA splicing (putative)
2) DNA-binding (putative)
3) component of a tri-snRNP complex
Compartment: found in the nucleus of proliferating cells
Alternative splicing: named isoforms=1
Expression: ubiquitously expressed
General
DNA-binding protein
phosphoprotein
U4/U6.U5 tri-snRNP-associated protein
Properties
SIZE: MW = 90 kD
entity length = 800 aa
COMPARTMENT: cell nucleus
MOTIF: coiled coil {157-231}
Thr phosphorylation site {T392}
RNA-binding motif
FOR-BINDING-OF: ribonucleic acid
DNA-binding motif
coiled coil {490-533}
Database Correlations
OMIM 605941
UniProt O43290
Pfam PF03343
References
UniProt :accession O43290
Component-of
spliceosome C complex