U3 small nucleolar ribonucleoprotein protein IMP3 homolog; U3 snoRNP protein IMP3; BRMS2 (IMP3, C15orf12, MRPS4)

Function: - component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). required for the early cleavages during pre-18S ribosomal RNA processing - component of a heterotrimeric complex containing IMP3, IMP4 & MPHOSPH10 - interacts with MPHOSPH10 Structure: - belongs to the ribosomal protein S4P family - contains 1 S4 RNA-binding domain Compartment: nucleus, nucleolus

General

nuclear protein RNA-binding protein

Properties

SIZE: entity length = 184 aa MW = 22 kD COMPARTMENT: cell nucleus MOTIF: arginine-rich region {32-74} MOTIF: arginine residue (SEVERAL) RNA-binding motif SITE: 109-175 FOR-BINDING-OF: ribonucleic acid

Database Correlations

OMIM 612980 UniProt Q9NV31 Pfam PF01479 Entrez Gene 55272 Kegg hsa:55272

References

UniProt :accession Q9NV31