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U11/U12 small nuclear ribonucleoprotein 35 kD protein; U11/U12 snRNP 35 kD protein; U11/U12-35K; U1 snRNP-binding protein homolog; protein HM-1 (SNRNP35, U1SNRNPBP, HM1)
Function:
- component of the U11/U12 snRNPs that are part of the U12-type spliceosome
Structure: contains 1 RRM (RNA recognition motif) domain
Compartment: nucleus
Alternative splicing: named isoforms=2
Expression:
- expressed in heart, liver, skeletal muscle & pancreas
General
nuclear protein
Properties
SIZE: entity length = 246 aa
MW = 29 kD
COMPARTMENT: cell nucleus
MOTIF: RNP motif
NAME: RNP motif
SITE: 51-129
FOR-BINDING-OF: ribonucleic acid
MOTIF: ribonucleoprotein-1 motif
NAME: ribonucleoprotein-1 motif
FOR-BINDING-OF: ribonucleic acid
MOTIF: ribonucleoprotein-1 motif
ribonucleoprotein-2 motif
ribonucleoprotein-2 motif
FOR-BINDING-OF: ribonucleic acid
MOTIF: ribonucleoprotein-1 motif
ribonucleoprotein-2 motif
arginine-rich region {154-244}
MOTIF: arginine residue (SEVERAL)
Database Correlations
UniProt Q16560
Pfam PF00076
References
UniProt :accession Q16560