U1-snRNP; U1 small nuclear ribonucleoprotein

U1 binds to 5'splice site.

Properties

COMPARTMENT: cell nucleus SUBUNITS: U1-snRNA MOTIF: Sm binding site EFFECTOR-BOUND: Sm protein BOUND-VIA: RNA-binding motif inverted GTP 5' cap structure 2,2,7 trimethylated inverted GTP 5' cap structure U1-A protein MOTIF: RNP motif NAME: RNP motif FOR-BINDING-OF: ribonucleic acid MOTIF: ribonucleoprotein-1 motif ribonucleoprotein-2 motif U1 70 kD protein MOTIF: RNP motif NAME: RNP motif FOR-BINDING-OF: ribonucleic acid MOTIF: ribonucleoprotein-1 motif ribonucleoprotein-2 motif Ser phosphorylation site U1-C protein MOTIF: RNA-binding motif FOR-BINDING-OF: ribonucleic acid U1/U2-E protein nuclear protein

References

- Bindereif A, Wolff T, Green MR. Discrete domains of human U6 snRNA required for the assembly of U4/U6 snRNP and splicing complexes. EMBO J. 1990 Jan;9(1):251-5. PMID: 2136831

Components

nuclear protein U1 70 kD protein (SNRNP70) U1-A protein (SNRPA) U1-C protein; U1 snRNP C (SNRPC) U1-snRNA U1/U2-E protein (snRPE)