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T-spot.TB

Indications: - tuberculosis Advantages: - no need for 2nd visit Disadvantages: - false positives among healthcare workers more frequent (5.0%) than tuberculin skin testing (1.8%) [2] - test conversion among healthcare workers more frequent (8.3%) than with tuberculin skin testing (0.9%) [2] * no association between test conversion & exposure to tuberculosis [2] Method: includes positive control

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tuberculosis

General

laboratory tests for tuberculosis

References

  1. Ferrara G et al, Use in routine clinical practice of two commercial blood tests for diagnosis of infection with Mycobacterium tuberculosis. Lancet 2006; 367:1328 PMID: 16631911
  2. Dorman SE et al. Interferon-gamma release assays and tuberculin skin testing for diagnosis of latent tuberculosis infection in healthcare workers in the United States. Am J Respir Crit Care Med 2014 Jan 1; 189:77 PMID: 24299555