Search
T-cell immunomodulatory protein (protein TIP, integrin-alpha FG-GAP repeat-containing protein 1, ITFG1, TIP, CDA08)
Function:
- modulator of T-cell function
- protective effect in graft versus host disease model (putative)
Structure:
- belongs to the TIP family
- contains 1 FG-GAP repeat
Compartment: secreted, membrane
Expression: ubiquitously expressed
Related
integrin-alpha FG-GAP repeat-containing protein 2 (ITFG2)
General
glycoprotein
membrane protein
secreted protein
Properties
SIZE: MW = 68 kD
entity length = 612 aa
COMPARTMENT: cellular membrane
MOTIF: signal sequence {1-33}
N-glycosylation site {N36}
N-glycosylation site {N95}
N-glycosylation site {N139}
N-glycosylation site {N146}
N-glycosylation site {N151}
N-glycosylation site {N176}
N-glycosylation site {N188}
N-glycosylation site {N226}
N-glycosylation site {N243}
FG-GAP {258-293}
N-glycosylation site {N353}
N-glycosylation site {N371}
N-glycosylation site {N482}
transmembrane domain {567-587}
Database Correlations
UniProt Q8TB96
Pfam PF01839
References
UniProt :accession Q8TB96