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T-cell immunoglobulin & mucin domain-containing protein 4 (TIMD-4, T-cell membrane protein 4, TIM-4, TIMD4, TIM4)
Function:
1) regulation of T-cell proliferation & lymphotoxin signaling
2) ligand for HAVCR1/TIMD1
Compartment: membrane
General
glycoprotein
membrane protein
Properties
SIZE: MW = 42 kD
entity length = 378 aa
COMPARTMENT: cellular membrane
MOTIF: signal sequence {1-24}
immunoglobulin superfamily domain {25-126}
MOTIF: cysteine residue {C40}
MODIFICATION: cysteine residue {C112}
cysteine residue {C112}
MODIFICATION: cysteine residue {C40}
threonine-rich region {136-214}
MOTIF: threonine residue (SEVERAL)
serine-rich region {234-277}
MOTIF: serine residue (SEVERAL)
N-glycosylation site {N291}
transmembrane domain {315-335}
Database Correlations
UniProt Q96H15
Pfam PF07686
References
UniProt :accession Q96H15