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CD86, activation B7-2 antigen, B70, fun-1 or BU63
Function:
- involved in costimulatory signal for interleukin 2 production & T lymphocyte proliferation
- ligand for CD28, CD152
Expression:
- dendritic cells
- Langerhans cells
- memory B cells
- germinal center B cells, centrocytes > centroblasts
- monocytes, low levels
- activated T cells
- endothelial cells
General
cluster-of-differentiation antigen; cluster designation antigen; CD antigen
glycoprotein
immunoglobulin superfamily protein
receptor
Properties
COMPARTMENT: plasma membrane
CELL: T-cell
MOTIF: glycosylation site
ligand-binding site
membrane region
Database Correlations
OMIM 601020
UniProt P42081
Entrez Gene 942
References
- UniProt :accession P42081
- Entrez Gene :accession 942
- http://www.pathologyoutlines.com/cdmarkers.html
20 May 2003
- Protein Reviews on the Web
http://mpr.nci.nih.gov/prow/guide/354181017_g.htm