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T-box transcription factor TBX6; T-box protein 6 (TBX6)

Function: - probable transcriptional regulator involved in developmental processes - could be required for specification of paraxial mesoderm structures during gastrulation (putative) - forms a dimeric complex with DNA (in vitro) Structure: - contains 1 T-box DNA-binding domain Compartment: nucleus (putative) Expression: - expressed in fetal tail bud, posterior spinal tissue, intervertebral disk & testis - also expressed in adult testis, kidney, lung, muscle & thymus - expressed during gastrulation & during a second phase in some adult tissues

General

T-box (TBX) protein

Properties

SIZE: entity length = 436 aa MW = 47 kD COMPARTMENT: cell nucleus MOTIF: T-box domain SITE: 100-273

Database Correlations

OMIM 602427 UniProt O95947 Pfam PF00907 Entrez Gene 6911 Kegg hsa:6911

References

  1. UniProt :accession O95947
  2. Entrez Gene :accession 6911