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T-bet gene

In the mouse the T-bet gene is located on chromosome 11.

Related

T-bet knockout mouse T-box transcription factor TBX21; T-box protein 21; T-cell-specific T-box transcription factor T-bet; transcription factor TBLYM (TBX21, TBET, TBLYM)

General

unclassified gene

Properties

TEMPLATE-FOR: messenger RNA TEMPLATE-FOR: T-box transcription factor TBX21 MOTIF: transcription factor binding site transcriptional start site exon intron transcriptional termination site

References

  1. Finotto S et al, Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet. Science 295:336, 2002 PMID: 11786643
  2. Szabo SJ et al, Distinct effects of T-bet in TH1 lineage commitment of IFN-gamma production in CD4 and CD8 T cells. Science 295:338, 2002 PMID: 11786644
  3. Vogel G, Asthma research. Missing gene takes mice's breath away. Science 295:253, 2002 PMID: 11786617