Search
tweety homolog 3 (hTTY3) (TTYH3 KIAA1691)
Function:
- probable large-conductance Ca+2-activated chloride channel
- may play a role in Ca+2 signal transduction
Structure:
- belongs to the tweety family
Compartment: cell membrane
Alternative splicing: named isoforms=3
Expression:
- expressed in excitable tissues
- expressed in brain, heart, skeletal muscle, colon, spleen, kidney & peripheral blood leukocytes
General
glycoprotein
phosphoprotein
transmembrane 5 protein
tweety homolog
Properties
SIZE: entity length = 523 aa
MW = 58 kD
COMPARTMENT: cell nucleus
MOTIF: exoplasmic domain {1-42}
transmembrane domain {43-63}
cytoplasmic loop {64-86}
transmembrane domain {87-107}
exoplasmic loop {108-211}
MOTIF: N-glycosylation site {N126}
N-glycosylation site {N144}
transmembrane domain {212-232}
cytoplasmic loop {233-236}
transmembrane domain {237-257}
exoplasmic loop {258-386}
MOTIF: N-glycosylation site {N351}
transmembrane domain {387-407}
cytoplasmic domain {408-523}
MOTIF: Ser phosphorylation site {S504}
Ser phosphorylation site {S522}
Database Correlations
OMIM 608919
UniProt Q9C0H2
Pfam PF04906
References
UniProt :accession Q9C0H2