tetraspanin-8; Tspan-8; transmembrane 4 superfamily member 3; tumor-associated antigen CO-029 (TSPAN8, TM4SF3)

Structure: belongs to the tetraspanin (TM4SF) family Compartment: membrane Pathology: - expressed in gastric cancer, colorectal carcinomas, & pancreatic carcer

General

antigen tetraspanin (transmembrane-4-superprotein)

Properties

SIZE: entity length = 237 aa MW = 26 kD COMPARTMENT: cellular membrane MOTIF: cytoplasmic domain {1-9} transmembrane domain {10-33} exoplasmic loop {34-57} transmembrane domain {58-72} cytoplasmic loop {73-83} transmembrane domain {84-109} exoplasmic loop {110-205} MOTIF: N-glycosylation site {N118} transmembrane domain {206-230} cytoplasmic domain {231-237}

Database Correlations

OMIM 600769 UniProt P19075 Pfam PF00335 Entrez Gene 7103 Kegg hsa:7103

References

UniProt :accession P19075