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tropsium
Indications:
- used in combination with xanomeline for treatment of schizophrenia
Adverse effects:
- peripheral anticholinergic adverse effects
Mechanism of action:
- peripheral muscarinic receptor antagonist
- reduces peripheral cholinergic effects of xanomeline
Interactions
drug adverse effects of parasympatholytics
General
parasympatholytic (anticholinergic, antimuscarinic agent)
References
- Brannan SK, Sawchak S, Miller AC et al
Muscarinic Cholinergic Receptor Agonist and Peripheral Antagonist
for Schizophrenia.
N Engl J Med 2021; 384:717-726 Feb 25
PMID: 33626254
https://www.nejm.org/doi/full/10.1056/NEJMoa2017015B
Component-of
tropsium chloride/xanomeline (Cobenfy, KarXT)