Search
tropomodulin-4; skeletal muscle tropomodulin; Sk-Tmod (TMOD4)
Function:
- blocks elongation & depolymerization of actin filaments at the pointed end
- the Tmod/TM complex contributes to formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton
- binds to the N-terminus of tropomyosin & to actin
Structure: belongs to the tropomodulin family
Compartment: cytoplasm, cytoskeleton
Expression: highly expressed in skeletal msucle
General
tropomodulin
Properties
SIZE: entity length = 345 aa
MW = 39 kD
COMPARTMENT: cytoplasm
Database Correlations
OMIM 605834
UniProt Q9NZQ9
Pfam PF03250
Entrez Gene 29765
Kegg hsa:29765
References
UniProt :accession Q9NZQ9