tropomodulin-3; ubiquitous tropomodulin; U-Tmod (TMOD3)

Function: - blocks elongation & depolymerization of actin filaments at the pointed end - the Tmod/TM complex contributes to formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton (putative) - binds to the N-terminus of tropomyosin & to actin Structure: belongs to the tropomodulin family Compartment: cytoplasm, cytoskeleton (putative) Expression: ubiquitous

General

phosphoprotein tropomodulin

Properties

SIZE: entity length = 352 aa MW = 40 kD COMPARTMENT: cytoplasm MOTIF: Ser phosphorylation site {S25} Ser phosphorylation site {S71}

Database Correlations

OMIM 605112 UniProt Q9NYL9 Pfam PF03250 Entrez Gene 29766 Kegg hsa:29766

References

UniProt :accession Q9NYL9