tropomodulin-2; neuronal tropomodulin; N-Tmod (TMOD2, NTMOD)

Function: - blocks elongation & depolymerization of actin filaments at the pointed end - the Tmod/TM complex contributes to formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton (putative) - binds to the N-terminus of tropomyosin & to actin Structure: belongs to the tropomodulin family Compartment: cytoplasm, cytoskeleton (putative) Expression: neuronal-tissue specific

General

phosphoprotein tropomodulin

Properties

SIZE: entity length = 351 aa MW = 40 kD COMPARTMENT: cytoplasm MOTIF: phosphorylation site

Database Correlations

OMIM 602928 UniProt Q9NZR1 Pfam PF03250 Entrez Gene 29767

References

UniProt :accession Q9NZR1