Tripterygium wilfordii Hook F (thunder god vine, lei gong teng)

Uses: - traditional Chinese medicine to treat inflammatory conditions - may be of benefit in rheumatoid arthritis Dose: - 180 mg (extract) PO QD - may be used in conjunction with prednisone Pharmacokinetics: - metabolites: triptolide, tripdiolide, & triptonide Mechanism of action: - anti-inflammatory - immunosuppressant

References

- Goldbach-Mansky R et al Comparison of Tripterygium wilfordii Hook F Versus Sulfasalazine in the Treatment of Rheumatoid Arthritis Annals of Internal Medicine 2009, 151:229-240 PMID: 19687490 http://www.annals.org/cgi/content/full/151/4/229