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trinucleotide repeat expansion disease

Pathology: - in myotonic dystrophy (1 & 2), MBNL3 colocalizes with nuclear foci of retained expanded-repeat transcripts

Specific

fragile X syndrome Friedreich ataxia myotonic dystrophy; Steinert disease; myotonia dystrophica neuronal intranuclear inclusion disease (NIID) polyalanine expansion disorder polyglutamine expansion disorder

General

genetic disease