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Trem-like transcript 2 protein (TLT-2, triggering receptor expressed on myeloid cells-like protein 2, TREML2, C6orf76, TLT2, UNQ6268/PRO20473)
Function:
- cell surface receptor
- role in the innate & adaptive immune response (putative)
Structure: contains 1 Ig-like V-type domain (immunoglobulin-like)
Compartment: cell membrane
Expression: detected in cultured B cells
Pathology:
- detected in T cell leukemia & monocytic leukemia
General
cell surface receptor
Properties
SIZE: MW = 35 kD
entity length = 321 aa
COMPARTMENT: plasma membrane
MOTIF: signal sequence {1-18}
immunoglobulin superfamily domain {20-121}
MOTIF: cysteine residue {C41}
MODIFICATION: cysteine residue {C105}
cysteine residue {C56}
MODIFICATION: cysteine residue {C63}
cysteine residue {C63}
MODIFICATION: cysteine residue {C56}
N-glycosylation site {N89}
cysteine residue {C105}
MODIFICATION: cysteine residue {C41}
transmembrane domain {269-289}
Database Correlations
UniProt Q5T2D2
Pfam PF07686
References
UniProt :accession Q5T2D2