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trauma/exercise/surgery & osteoarthritis
Trauma, acute or chronic, plays a role in both primary & secondary osteoarthritis, including:
1) repetitive motions causing pain
2) obesity
3) running does not cause osteoarthritis in previously normal joints, but does increase subchondral bone & marginal osteophytes
4) running on a hip or knee with previous osteoarthritis will accelerate the pathology
5) meniscectomy of the knee is associated with a 50% incidence of osteoarthritis after 15 years
References
Medical Knowledge Self Assessment Program (MKSAP) 11, American
College of Physicians, Philadelphia 1998